Good question. So far I haven’t put any effort to make sure it picks a discrete graphics card over an integrated one. That’s because my daily driver machine only has an integrated graphics card and I am mostly interested in retro gaming. In future, I plan to take a look into this.

Wine Bar does support Proton, and should it use hardware acceleration by default, it may be all you need. Give it a try and tell me how it went!

I tried Bottles a long time ago, on a regular x86_64 distro. I remember it suffered from the same problem I described above: it either works out of the box or not at all, and you can’t do anything about it.

On my Macbook Air I couldn’t try Bottles at all, as the version from the repo doesn’t install (complains about x86-32 dependencies not being available) and the project doesn’t provide an AppImage that I could extract and try running under muvm, as I did with Heroic.