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Joined 6 months ago
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Cake day: June 1st, 2025

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  • Something i have thought about for some time. Do we only have one consciousness? Like if you literally split your brain in half via operation suddenly you got two brain halves tha’t can not communicate with each other in any way. Do you now have 2 personalities and consciousness? If yes, why don’t you have them before? Maybe you always have two but they are just in agreement. And why stop at two? There are some interviews with siamese twins (the teacher sisters for example) and it’s so interesting to see how they talk. They finish each other sentences which is natural i guess but they also say “ehh” when the other one doesn’t know a word. It’s like a single person talking. I am not arguing they are distinctive persons. Just some random thoughts.


  • Contact info gets hashed in a clever way which doesn’t send your info (although i guess phone number hashes could be brute forced?) Meta data is also not available. They have no way to know who you are talking to. The only info they have is that you logged ij with a ip at a time. I believe they can’t even reliable track how many messages you send. Even with a compromised server most of the magic happens in the open source client side app so that they can’t gather very much. I understand your concerns about popular centralized services but i really believe that they are unfound with signal.



  • Can’t read the whole article due to paywall. Here are 2 thoughts for the half that i did read.

    • colorectal cancer makes a lot of sense as a target. it still is one of the most cancers with the highest mortality. At the same time we saw an uptick in colorectal cancer rates in young people (reason unknown, maybe microplastics maybe something else.). Furthemore colorectal cancer seems to be a great target for immunsystem modulating therapy. There was a paper 3 years bake in I think the NEJM where they put 18/18 (exact N not sure) patients in remission with PD-1 modulation which also activates the immun system.

    • Astra Zeneca (I believe) is also working on a mRNA vaccine for cancer that is quite far along. They are targeting melanoma in remission and reduced reoccurence of melanoma or metastasis after 3 years by 50%. So it seems like mRNA cancer vaccines will be a strong pillar for future cancer treatements.

    Sadly we saw in the past that russia sometimes bolsters their numbers for medication efficency. I hope it is not the case this time but i hope that the phase 2/3 trials will be very transparent to quench any doubts.